Gastric carcinosarcoma (sarcomatoid carcinoma) with rhabdomyoblastic and osteoblastic differentiation.

摘要: A rare case of carcinosarcoma (sarcomatoid carcinoma) with rhabdomyoblastic and osteoblastic differentiation occurring in the gastric remnant is reported. 69-year-old Japanese man who had undergone a partial gastrectomy for duodenal ulcer 30 years earlier, presented anemia, epigastralgia, an abdominal mass. The diagnosis was made based on findings endoscopic biopsies. patient thus scheduled to undergo surgical operation, but he died respiratory failure. At autopsy, huge polypoid tumor measuring 20 x 18 8 cm located greater curvature remnant. Microscopically, consisted intimately mixed tubular adenocarcinoma heterologous mesenchymal elements containing rhabdomyosarcoma osteosarcoma. Between these components, morphological transition from element sarcomatous observed. Ultrastructually, confirmed areas. Immunocytochemical expressions epithelial markers including membrane antigen cytokeratins (35bH11 34bE12) were recognized not only carcinomatous cells also cells. These suggest that appear transform into features.