Process for the production of a chimera monoclonal antibody
作者： Masaru Taniguchi , Kou-Zou Sugita , Yoshikazu Lions Mansion Kurosawa
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摘要: This invention concerns a animal-human chimera monoclonal antibody whose side-effects such as anaphylaxis and serum sickness are thought to be greatly reduced when it is administered man. The consists of variable region derived from experimental animals constant production process the characterized by comprising inserting active chimeric Ig heavy light chain genes into an expression vector then introducing them cultured animal cells.
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