Radiation-induced heart disease in rats
作者： Susanne Lauk , Zoltan Kiszel , Johannes Buschmann , Klaus-Rüdiger Trott
DOI: 10.1016/0360-3016(85)90314-1
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摘要: After local irradiation of the rat heart with X ray doses over 10 Gy (single dose), animals developed symptoms radiation-induced disease, which at higher would lead to fatal cardiac failure. The LD 50 1 year was between 15 and 20 Gy. pericardium epicardium responded exudative pericarditis after 4 months. Focal myocardial damage secondary progressive capillary damage.
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sci-hub.se 参考文章(11)
L.F. Fajardo, J.R. Stewart, K.E. Cohn, Morphology of radiation-induced heart disease. Archives of pathology. ,vol. 86, pp. 512- 519 ,(1968)
L. F. Fajardo, J. R. Stewart, Experimental radiation-induced heart disease. I. Light microscopic studies. American Journal of Pathology. ,vol. 59, pp. 299- 316 ,(1970)
R. Byhardt, K. Brace, J. Ruckdeschel, P. Chang, R. Martin, P. Wiernik, Dose and treatment factors in radiation related pericardial effusion associated with the mantle technique for Hodgkin's disease Cancer. ,vol. 35, pp. 795- 802 ,(1975) , 10.1002/1097-0142(197503)35:3<795::AID-CNCR2820350335>3.0.CO;2-M
ALDRED S. WARTHIN, ERNST A. POHLE, THE EFFECT OF ROENTGEN RAYS ON THE HEART: I. THE MICROSCOPIC CHANGES IN THE HEART MUSCLE OF RATS AND RABBITS FOLLOWING A SINGLE EXPOSURE JAMA. ,vol. 89, pp. 1825- 1829 ,(1927) , 10.1001/JAMA.1927.02690220001001
Adam Michalowski, Effects of radiation on normal tissues: hypothetical mechanisms and limitations of in situ assays of clonogenicity. Radiation and Environmental Biophysics. ,vol. 19, pp. 157- 172 ,(1981) , 10.1007/BF01324183
J. Robert Stewart, Luis F. Fajardo, Keith E. Cohn, Vera Page, Experimental Radiation-Induced Heart Disease in Rabbits Radiology. ,vol. 91, pp. 814- 817 ,(1968) , 10.1148/91.4.814
ALDRED S. WARTHIN, THE EFFECT OF ROENTGEN RAYS ON THE HEART Archives of Internal Medicine. ,vol. 43, pp. 15- 34 ,(1929) , 10.1001/ARCHINTE.1929.00130240018002
Klaus-Rüdiger Trott, CHRONIC DAMAGE AFTER RADIATION THERAPY: CHALLENGE TO RADIATION BIOLOGY International Journal of Radiation Oncology Biology Physics. ,vol. 10, pp. 907- 913 ,(1984) , 10.1016/0360-3016(84)90394-8
Williams, Late effect of high voltage roentgen rays on the heart of adult rats American Heart Journal. ,vol. 25, pp. 568- ,(1943) , 10.1016/S0002-8703(43)90526-5
J. Robert Stewart, Keith E. Cohn, Luis F. Fajardo, E. William Hancock, Henry S. Kaplan, RADIATION-INDUCED HEART DISEASE. A STUDY OF TWENTY-FIVE PATIENTS. Radiology. ,vol. 89, pp. 302- 310 ,(1967) , 10.1148/89.2.302