作者: Masahiro Yamada , Hiroshi Egusa
DOI: 10.1016/J.JPOR.2017.08.010
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摘要: Abstract Purpose Alveolar ridge augmentation is essential for success in implant therapy and depends on the biological performance of bone graft materials. This literature review aims to comprehensively explain clinically relevant capabilities limitations currently available substitutes light biomaterial science. Study selection The calcium phosphate-based was categorized according space-making capability, biocompatibility, bioabsorption, volume maintenance over time. Each category reviewed based clinical studies, preclinical animal vitro studies. Results Currently provide only osteoconduction as a scaffold but not osteoinduction. Particle size, sensitivity enzymatic or chemical dissolution, mechanical properties affect capability substitutes. nature collagen fibers, particulate release ions influence biocompatibility Bioabsorption determined by water solubility (chemical composition) acid resistance (integrity apatite structure). remnant substitute material augmented are inversely related. Conclusion It necessary improve strike an appropriate balance between bioabsorption achieve ideal remodeling.