Proteases in MHC Class I Presentation and Cross-Presentation

摘要: Cells that have mutated their genes or are virally infected a potential threat to host. Consequently, the immune system has evolved mechanisms for CD8 T lymphocytes identify such cells and eliminate them. The generation of cell responses occurs in two phases, both which critically involve process Ag presentation. In first phase, sentinel gather Ags present tissues then them naive ways stimulate maturation into effectors. second these effector seek out pathological cells. abnormal identified through presentation immunogenic they producing. used by can be different from those other This article will review with focus each case on how antigenic peptides generated