Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma.
作者： Yasuhiko Kitadai , Takamitsu Sasaki , Toshio Kuwai , Toru Nakamura , Corazon D. Bucana
DOI: 10.2353/AJPATH.2006.060653
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摘要: … (VEGF) pathway to inhibit tumor angiogenesis is attracting attention as a novel cancer therapy 45 ; however, it has been suggested that VEGF… PDGF-R and VEGF receptor signaling may …
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William J. LaRochelle, Michael Jeffers, William F. McDonald, Rajeev A. Chillakuru, Neill A. Giese, Nathalie A. Lokker, Carol Sullivan, Ferenc L. Boldog, Meijia Yang, Corine Vernet, Catherine E. Burgess, Elma Fernandes, Lisa L. Deegler, Beth Rittman, Juliette Shimkets, Richard A. Shimkets, Jonathan M. Rothberg, Henri S. Lichenstein, PDGF-D, a new protease-activated growth factor Nature Cell Biology. ,vol. 3, pp. 517- 521 ,(2001) , 10.1038/35074593
Mats Sjöquist, Carl-Henrik Heldin, Kristofer Rubin, Arne Ostman, Tobias Sjöblom, Elisabeth Buchdunger, Kristian Pietras, Inhibition of PDGF Receptor Signaling in Tumor Stroma Enhances Antitumor Effect of Chemotherapy Cancer Research. ,vol. 62, pp. 5476- 5484 ,(2002)
Motowo Nakajima, Sen Pathak, Isaiah J. Fidler, Kiyoshi Morikawa, J. Milburn Jessup, Shirley M. Walker, Influence of Organ Environment on the Growth, Selection, and Metastasis of Human Colon Carcinoma Cells in Nude Mice Cancer Research. ,vol. 48, pp. 6863- 6871 ,(1988)
Isabelle Barbieux, Blandine Lieubeau, Marc Gregoire, Khaled Meflah, Laure Garrigue, The Role of Transforming Growth Factor β1 in the Fibroblastic Reaction Associated with Rat Colorectal Tumor Development Cancer Research. ,vol. 54, pp. 6526- 6532 ,(1994)
Tailoi Chan-Ling, Matthew Philip Page, Tom Gardiner, Louise Baxter, Emilia Rosinova, Suzanne Hughes, Desmin Ensheathment Ratio as an Indicator of Vessel Stability The American Journal of Pathology. ,vol. 165, pp. 1301- 1313 ,(2004) , 10.1016/S0002-9440(10)63389-5
Lance A. Liotta, Elise C. Kohn, The microenvironment of the tumour-host interface Nature. ,vol. 411, pp. 375- 379 ,(2001) , 10.1038/35077241
R M Shaheen, S A Ahmad, W Liu, N Reinmuth, Y D Jung, W W Tseng, K E Drazan, C D Bucana, D J Hicklin, L M Ellis, Inhibited growth of colon cancer carcinomatosis by antibodies to vascular endothelial and epidermal growth factor receptors British Journal of Cancer. ,vol. 85, pp. 584- 589 ,(2001) , 10.1054/BJOC.2001.1936
Corazon D. Bucana, Jerald J. Killion, Kenji Yokoi, Douglas B. Evans, Rachel Tsan, Isaiah J. Fidler, Rosa Frances Hwang, Inhibition of Platelet-Derived Growth Factor Receptor Phosphorylation by STI571 (Gleevec) Reduces Growth and Metastasis of Human Pancreatic Carcinoma in an Orthotopic Nude Mouse Model Clinical Cancer Research. ,vol. 9, pp. 6534- 6544 ,(2003)
Hisanori Uehara, Takashi Karashima, Jerald J. Killion, Sun Jin Kim, Isaiah J. Fidler, David L. Shepherd, Blockade of epidermal growth factor receptor signaling in tumor cells and tumor-associated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice. Clinical Cancer Research. ,vol. 9, pp. 1200- 1210 ,(2003)
Kristian Pietras, Increasing tumor uptake of anticancer drugs with imatinib Seminars in Oncology. ,vol. 31, pp. 18- 23 ,(2004) , 10.1053/J.SEMINONCOL.2004.03.036