摘要: Publisher Summary This chapter discusses the factors adversely affecting placental transfer and their possible implications on fetal metabolism development. A distinguishing feature of mammalian development is provision nutrients from maternal organism. Adequate exchange across placenta between circulations essential for normal growth. The unique in its function several points view. Its lifetime short relative to fetus, size change continually during course gestation. For serves as lung, gastrointestinal tract, kidneys, liver, even endocrine organ. morphology changes gestation ways that could only be termed pathological any other Innumerable substances are transferred circulations. rates mechanisms vary different substances. Either physiological limitations or may affect rate various by cells. Alterations either acute chronic associated with chorion amnion per se. term insufficiency used often a clinical sense imply abnormal some specific alteration heart pattern. Maternal include decreases blood constituents uteroplacental flow. Placental abnormalities trophoblast vascular tissues, which primary secondary abnormalities. Fetal alterations umbilical