The phytoestrogen, diosgenin, directly stimulates ovarian cell functions in two farm animal species
作者： A.V. Sirotkin , R. Alexa , S. Alwasel , A.H. Harrath
DOI: 10.1016/J.DOMANIEND.2019.04.002
关键词:
摘要: The present in vitro study was conducted to examine the direct action of the plant steroidal sapogenin, diosgenin, on basic farm animal ovarian cell functions. As models, we used cultured porcine ovarian granulosa cells, porcine whole follicles, and rabbit ovarian fragments. The effects of diosgenin (0, 1, 10, or 100 μg/mL medium) on the markers of proliferation, cytoplasmic apoptosis, steroid (progesterone: P4, testosterone: T, and estradiol: E2) release, and peptide hormone (insulin-like growth factor I: IGF-I) release were …
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