Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

作者: Apostolia-Maria Tsimberidou , Michael J. Keating

DOI: 10.1007/978-1-4614-5197-6_20

关键词:

摘要: Chronic lymphocytic leukemia (CLL) and small lymphoma (SLL) are B-cell lymphoproliferative disorders characterized by a proliferation of mature-appearing but functionally incompetent lymphocytes. The result this is an accumulation lymphocytes that progressively infiltrate the lymph nodes, bone marrow, liver, spleen. CLL SLL classified World Health Organization as same disease entity [1]. They identical histologically immunophenotypically, their manifestation different: manifests primarily in peripheral blood or marrow nodes.

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