Expression of immune-related genes of Nile tilapia Oreochromis niloticus after Gyrodactylus cichlidarum and Cichlidogyrus sclerosus infections demonstrating immunosupression in coinfection
作者： Tingting Zhi , Xiangli Xu , Jinsong Chen , Yingying Zheng , Shuai Zhang
DOI: 10.1016/J.FSI.2018.05.060
关键词:
摘要: Abstract Gyrodactylus cichlidarum and Cichlidogyrus sclerosus, two monogenean ectoparasite species commonly found on the body surface gills of Nile tilapia (Oreochromis niloticus) respectively, inflicted considerable economic losses in intensive farming. In order to explore immune response against these monogeneans, expression patterns five immune-related genes were studied after singular G. or C. sclerosus infection their coinfection. The transcription levels IL-1β up-regulated skin infection, reaching a peak at day 5 PI, (peaking 8 PI), with significant elevation only detected high-dose infection. A trend favoring increased gill TNF-α PI was statistically low-dose group. did not change significantly TGF-β had extremely expressions both high- infections, but its promoted observed cichlidarum. Significantly HSP70 COX-2 infections. comparison either concurrent resulted advanced gills, lower similar gills. down-regulated TNF-α, addition, intensity positively correlated that (correlation index 0.922, p = 0.000) 2 under These results contribute understanding mucosal immunity fish particularly when infect concurrently.
cabdirect.org
elsevier.com
sci-hub.se 参考文章(51)
Reiko Horai, Susumu Nakae, Aya Nambu, Yoichiro Iwakura, Yutaka Komiyama, Masahide Asano, Akio Nakane, The Role of IL-1 in the Immune System Humana Press, Totowa, NJ. pp. 95- 109 ,(2003) , 10.1007/978-1-59259-405-4_6
I Paperna, Parasites, infections and diseases of fishes in Africa: An update. CIFA Technical Paper (FAO). no. 31.. ,(1996)
Francisco J. Roca, Iván Mulero, Azucena López-Muñoz, Maria P. Sepulcre, Stephen A. Renshaw, José Meseguer, Victoriano Mulero, Evolution of the Inflammatory Response in Vertebrates: Fish TNF-α Is a Powerful Activator of Endothelial Cells but Hardly Activates Phagocytes Journal of Immunology. ,vol. 181, pp. 5071- 5081 ,(2008) , 10.4049/JIMMUNOL.181.7.5071
T Lindenstrøm, K Buchmann, C.J Secombes, Gyrodactylus derjavini infection elicits IL-1β expression in rainbow trout skin. Fish & Shellfish Immunology. ,vol. 15, pp. 107- 115 ,(2003) , 10.1016/S1050-4648(02)00142-0
Cheng Lu, Fei Ling, Jie Ji, Yu-Jun Kang, Gao-Xue Wang, Expression of immune-related genes in goldfish gills induced by Dactylogyrus intermedius infections. Fish & Shellfish Immunology. ,vol. 34, pp. 372- 377 ,(2013) , 10.1016/J.FSI.2012.11.004
Andrew R. Bridle, Richard N. Morrison, Barbara F. Nowak, The expression of immune-regulatory genes in rainbow trout, Oncorhynchus mykiss, during amoebic gill disease (AGD). Fish & Shellfish Immunology. ,vol. 20, pp. 346- 364 ,(2006) , 10.1016/J.FSI.2005.05.014
Amy B. Pedersen, Andy Fenton, Emphasizing the ecology in parasite community ecology. Trends in Ecology and Evolution. ,vol. 22, pp. 133- 139 ,(2007) , 10.1016/J.TREE.2006.11.005
E FALIEX, C DASILVA, G SIMON, P SASAL, Dynamic expression of immune response genes in the sea bass, Dicentrarchus labrax, experimentally infected with the monogenean Diplectanum aequans Fish & Shellfish Immunology. ,vol. 24, pp. 759- 767 ,(2008) , 10.1016/J.FSI.2008.02.011
Ewa Mariéthoz, Fabienne Tacchini-Cottler, Muriel Jacquier-Sarlln, Fiona Sinclair, Barbara S. Polia, Exposure of monocytes to heat shock does not increase class II expression but modulates antigen-dependent T cell responses International Immunology. ,vol. 6, pp. 925- 930 ,(1994) , 10.1093/INTIMM/6.6.925
Kurt Buchmann, T Lindenstrøm, Interactions between monogenean parasites and their fish hosts. International Journal for Parasitology. ,vol. 32, pp. 309- 319 ,(2002) , 10.1016/S0020-7519(01)00332-0