Generation of superoxide anions by leucocytes treated with cytochalasin E

作者: Akira Nakagawara , Shigeki Minakami

DOI: 10.1016/0006-291X(75)90385-X

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摘要: Abstract Guinea pig polymorphonuclear leucocytes reduced cytochrome c when treated with cytochalasin E. The reduction was completely inhibited by superoxide dismutase and manganese ions, which indicates that anions are generated released into the outside medium treatment. glycolytic inhibitors cyclic AMP but not GMP. pattern is similar to cyanide-insensitive respiration of during phagocytosis. Nitroblue tetrazolium also cytochalasin, only partially dismutase.

参考文章(14)
Koichiro TAKESHIGE, Akira NAKAGAWARA, Tanenori HATAE, Shigeki MINAKAMI, Metabolic pattern of polymorphonuclear leucocytes induced by trypsin-digested microsomes. Journal of Biochemistry. ,vol. 77, pp. 559- 566 ,(1975) , 10.1093/OXFORDJOURNALS.JBCHEM.A130756
Anthony J. Sbarra, Manfred L. Karnovsky, The biochemical basis of phagocytosis. I. Metabolic changes during the ingestion of particles by polymorphonuclear leukocytes. Journal of Biological Chemistry. ,vol. 234, pp. 1355- 1362 ,(1959) , 10.1016/S0021-9258(18)70011-2
Joseph W. DePierre, Manfred L. Karnovsky, Ecto-Enzymes of the Guinea Pig Polymorphonuclear Leukocyte Journal of Biological Chemistry. ,vol. 249, pp. 7111- 7120 ,(1974) , 10.1016/S0021-9258(19)42081-4
Akira NAKAGAWARA, Koichiro TAKESHIGE, Shigeki MINAKAMI, Effect of cyclic nucleotides on the cyanide-insensitive respiration of polymorphonuclear leucocytes. Journal of Biochemistry. ,vol. 77, pp. 567- 573 ,(1975) , 10.1093/OXFORDJOURNALS.JBCHEM.A130757
Joe M. McCord, Irwin Fridovich, Superoxide Dismutase AN ENZYMIC FUNCTION FOR ERYTHROCUPREIN (HEMOCUPREIN) Journal of Biological Chemistry. ,vol. 244, pp. 6049- 6055 ,(1969) , 10.1016/S0021-9258(18)63504-5
Fred J. Yost, Irwin Fridovich, Superoxide radicals and phagocytosis Archives of Biochemistry and Biophysics. ,vol. 161, pp. 395- 401 ,(1974) , 10.1016/0003-9861(74)90320-8
Marvin L. Salin, Joe M. McCord, Superoxide Dismutases in Polymorphonuclear Leukocytes Journal of Clinical Investigation. ,vol. 54, pp. 1005- 1009 ,(1974) , 10.1172/JCI107816
A. Nakagawara, K. Takeshige, S. Minakami, Induction of a phagocytosis-like metabolic pattern in polymorphonuclear leucocytes by cytochalasin E. Experimental Cell Research. ,vol. 87, pp. 392- 394 ,(1974) , 10.1016/0014-4827(74)90498-4