Innovative Rational-Derived, Target-Based and Cytotoxic Therapies for Breast Cancer and Other Malignancies

Julian Adams, Vito J. Palombella, Peter J. Elliott, Proteasome inhibition: a new strategy in cancer treatment. Investigational New Drugs. ,vol. 18, pp. 109- 121 ,(2000) , 10.1023/A:1006321828515

Roger J. Daly, Michele D. Binder, Robert L. Sutherland, OVEREXPRESSION OF THE GRB2 GENE IN HUMAN BREAST CANCER CELL LINES Oncogene. ,vol. 9, pp. 2723- 2727 ,(1994)

David W. Fry, Inhibition of the epidermal growth factor receptor family of tyrosine kinases as an approach to cancer chemotherapy: progression from reversible to irreversible inhibitors. Pharmacology & Therapeutics. ,vol. 82, pp. 207- 218 ,(1999) , 10.1016/S0163-7258(98)00050-3

Henning Walczak, Robert E. Miller, Kiley Ariail, Brian Gliniak, Thomas S. Griffith, Marek Kubin, Wilson Chin, Jon Jones, Anne Woodward, Tiep Le, Craig Smith, Pam Smolak, Raymond G. Goodwin, Charles T. Rauch, JoAnn C.L. Schuh, David H. Lynch, Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo Nature Medicine. ,vol. 5, pp. 157- 163 ,(1999) , 10.1038/5517

Judith S. Sebolt-Leopold, David T. Dudley, Roman Herrera, Keri Van Becelaere, Amy Wiland, Richard C. Gowan, Haile Tecle, Stephen D. Barrett, Alexander Bridges, Sally Przybranowski, W.R. Leopold, Alan R. Saltiel, Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nature Medicine. ,vol. 5, pp. 810- 816 ,(1999) , 10.1038/10533

Shinichi Kitada, Maryla Krajewska, Jurgita Sauvageot, Ahmed Shabaik, Stanislaw Krajewski, Jonathan I. Epstein, John C. Reed, Ki Song, Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers. American Journal of Pathology. ,vol. 148, pp. 1567- 1576 ,(1996)

F McPhillips, P Mullen, B P Monia, A A Ritchie, F A Dorr, J F Smyth, S P Langdon, Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer. British Journal of Cancer. ,vol. 85, pp. 1753- 1758 ,(2001) , 10.1054/BJOC.2001.2139

V. Bhargava, D. L. Kell, M. van de Rijn, R. A. Warnke, Bcl-2 immunoreactivity in breast carcinoma correlates with hormone receptor positivity. American Journal of Pathology. ,vol. 145, pp. 535- 540 ,(1994)

Timothy S. Lewis, Paul S. Shapiro, Natalie G. Ahn, Signal Transduction through MAP Kinase Cascades Advances in Cancer Research. ,vol. 74, pp. 49- 139 ,(1998) , 10.1016/S0065-230X(08)60765-4

Hayley M. McDaid, Thomas R.R. Pettus, Laura A. Martello, Susan Band Horwitz, Donna Lee Regl, Hirokazu Arimoto, Amos B. Smith, Michael D. Kaufman, Samuel J. Danishefsky, Chia Ping H. Yang, Dongfang Meng, Taxol and Discodermolide Represent a Synergistic Drug Combination in Human Carcinoma Cell Lines Clinical Cancer Research. ,vol. 6, pp. 1978- 1987 ,(2000)