Sterculia crosslinked PVA and PVA-poly(AAm) hydrogel wound dressings for slow drug delivery: mechanical, mucoadhesive, biocompatible and permeability properties.
作者： Lok Pal , Baljit Singh
DOI: 10.1016/J.JMBBM.2012.01.021
关键词:
摘要: The present study deals with the synthesis and characterization of sterculia crosslinked PVA PVA-AAm hydrogel wound dressings. hydrogels have been characterized by SEMs, FTIR, TGA swelling studies. This article also discusses comparison swelling, drug release biomedical properties such as blood compatibility, antimicrobial activity, mucoadhesion, tensile strength, burst water vapour permeability, oxygen diffusion microbial penetration both These polymeric films absorbed 4.80 ± 0.15 6.32 gram/g gel simulated fluid respectively occurred through Case II mechanism. antibiotic drugs non-Fickian mechanisms, respectively. observed to be permeable for but shown impermeability micro-organism. Sterculia-PVA dressing has more compatibility compared other film. All these results indicate that may used dressings slow wound.
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