作者: JASON L. LETRAN , AMY B. BLASE , FAUSTO R. LOBERIZA , GRANT E. MEYER , SEAN D. RANSOM
DOI: 10.1016/S0022-5347(01)62915-X
关键词:
摘要: AbstractPurpose: Despite being the most useful tumor marker for diagnosis of patients with prostate cancer, serum specific antigen (PSA) is still hampered by lack specificity. A negative biopsy associated a 20 to 40% incidence positive repeat in men persistently elevated PSA levels. We determine whether free-to-total ratio could be predictive cancer undergoing biopsy.Materials and Methods: Archival sera, drawn before first biopsy, were gathered from 51 total 2 15 ng./ml. who underwent needle various indications. The percent free was calculated using Hybritech Tandem-R [dagger] as well Dianon Systems [double dagger] assays. results between noncancer groups compared Student's t test.Results: median significantly...