作者: Theresa L. Whiteside
DOI: 10.1016/J.ORALONCOLOGY.2009.03.006
关键词:
摘要: Summary Tumor escape from the host immune system has been a major problem in immunotherapy of human malignancies. Human tumors are known to develop strategies, which might differ among same histology. This suggests that host-tumor interactions create tumor microenvironment is unique for every tumor. Recent advances cancer immunology allow better understanding mechanisms use execute and relationship establishes with cells. It now feasible obtain an “immune signature” tumor, define genetic, molecular functional profiles cells microenvironment. knowledge be critically important personalized selection available therapies thus clinical outcome.