Leptin fluctuates in intestinal ischemia-reperfusion injury as inflammatory cytokine.
作者： Ji Lin , Guang-Tao Yan , Lu-Huan Wang , Xiu-Hua Hao , Kai Zhang
DOI: 10.1016/J.PEPTIDES.2004.08.006
关键词:
摘要: As leptin is an active mediator mainly secreted by adipose tissue and closely related with energy metabolism, we evaluate both the changes of levels in serum a concise radioimmunoassay mRNA expression RT-PCR, during severe metabolic impediment rat intestinal ischemia-reperfusion (I/R) injury. Results show that not only but also its undergo fluctuation according to different injury times. Therefore, conclude has time-dependent response acute inflammatory stimuli acts as anti-inflammatory cytokine.
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