Studies on the anti-tumour activity of aliphatic aldehydes—III

摘要: The formation of a thiazolidine-4-carboxylic acid in normal and neoplastic tissues as result the condensation endogenous cysteine with an added aliphatic aldehyde (C14-labelled α,β-dihydroxybutyraldehyde) has been followed by electrophoretic-chromatographic methods on paper silica-gel thin-layer, radioactive scanning autoradiographic techniques. identification thiazolidine carboxylic acids treated aldehydes indicated that at expense occurred freely under physiological conditions reinforced previous evidence suggesting lowered availability tissue (and consequent imbalance protein-synthesizing amino pool) could explain inhibitory effect protein biosynthesis.