In vitro effectiveness of tea tree oil against Trichophyton equinum

作者: S. Nardoni , A. Bertoli , L. Pinto , F. Mancianti , F. Pisseri

DOI: 10.1016/J.MYCMED.2009.12.002

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摘要: Summary Essential oils from many plants are known to possess antifungal activity, but only limited information exists about activity towards human and animal fungal pathogens. The in vitro sensitivity of nine clinical isolates Trichophyton equinum tea tree oil (TTO) was evaluated by a microdilution test. As the quality chemical composition commercial essential Melaleuca alternifolia extremely variable, all samples were analyzed gas-chromatography mass spectrometry (GC-MS) before being used for assays. All showed minimum inhibitory concentrations (MICs) 2.5%, 4% yielded fungicidal effect. Compared other results reported literature, present findings indicate lesser susceptibility T. equinum, TTO. This fact could be explained different testing conditions, namely medium diluent employed.

参考文章(23)
S. D. Cox, C. M. Mann, J. L. Markham, H. C. Bell, J. E. Gustafson, J. R. Warmington, S. G. Wyllie, The mode of antimicrobial action of the essential oil of Melaleuca alternifolia (tea tree oil). Journal of Applied Microbiology. ,vol. 88, pp. 170- 175 ,(2001) , 10.1046/J.1365-2672.2000.00943.X
Sean C. Sweetman., Martindale: The Complete Drug Reference ,(1999)
F. Pisseri, A. Bertoli, S. Nardoni, L. Pinto, L. Pistelli, G. Guidi, F. Mancianti, Antifungal activity of tea tree oil from Melaleuca alternifolia against Trichophyton equinum: An in vivo assay Phytomedicine. ,vol. 16, pp. 1056- 1058 ,(2009) , 10.1016/J.PHYMED.2009.03.013
Joseph J. Brophy, Noel W. Davies, Ian A. Southwell, Ian A. Stiff, Lyall R. Williams, Gas chromatographic quality control for oil of Melaleuca terpinen-4-ol type (Australian tea tree) Journal of Agricultural and Food Chemistry. ,vol. 37, pp. 1330- 1335 ,(1989) , 10.1021/JF00089A027
A. Weseler, H.K. Geiss, R. Saller, J. Reichling, Antifungal effect of Australian tea tree oil on Malassezia pachydermatis isolated from canines suffering from cutaneous skin disease. Schweizer Archiv Fur Tierheilkunde. ,vol. 144, pp. 215- 221 ,(2002) , 10.1024/0036-7281.144.5.215
F.D. D'auria, L. Laino, V. Strippoli, M. Tecca, G. Salvatore, L. Battinelli, G. Mazzanti, In Vitro Activity of Tea Tree Oil Against Candida albicans Mycelial Conversion and Other Pathogenic Fungi Journal of Chemotherapy. ,vol. 13, pp. 377- 383 ,(2001) , 10.1179/JOC.2001.13.4.377
Laura E Homer, David N Leach, David Lea, L Slade Lee, Robert J Henry, Peter R Baverstock, Natural variation in the essential oil content of Melaleuca alternifolia Cheel (Myrtaceae) Biochemical Systematics and Ecology. ,vol. 28, pp. 367- 382 ,(2000) , 10.1016/S0305-1978(99)00071-X
Eugénia Pinto, Lígia Ribeiro Salgueiro, Carlos Cavaleiro, Ana Palmeira, Maria José Gonçalves, In vitro susceptibility of some species of yeasts and filamentous fungi to essential oils of Salvia officinalis Industrial Crops and Products. ,vol. 26, pp. 135- 141 ,(2007) , 10.1016/J.INDCROP.2007.02.004
KAREN A. MORIELLO, DOUGLAS J. DEBOER, LYNN M. VOLK, ANDREW SPARKES, ANN ROBINSON, Development of an in vitro, isolated, infected spore testing model for disinfectant testing of Microsporum canis isolates. Veterinary Dermatology. ,vol. 15, pp. 175- 180 ,(2004) , 10.1111/J.1365-3164.2004.00390.X