Antimicrobial drug development – the past, the present, and the future

作者: J.H. Powers

DOI: 10.1111/J.1465-0691.2004.1007.X

关键词:

摘要: … the history of antimicrobial drug development, how it has influenced the present situation, … adverse events associated with drug usage should be balanced by the benefits achieved by …

参考文章(13)
Marjan Najafi, Stacey L Knobler, Tom Burroughs, Stanley M Lemon, A Public Health Action Plan to Combat Antimicrobial Resistance National Academies Press (US). ,(2003)
Janice M. Reichert, Trends in development and approval times for new therapeutics in the United States. Nature Reviews Drug Discovery. ,vol. 2, pp. 695- 702 ,(2003) , 10.1038/NRD1178
John H. Powers, Development of drugs for antimicrobial-resistant pathogens. Current Opinion in Infectious Diseases. ,vol. 16, pp. 547- 551 ,(2003) , 10.1097/00001432-200312000-00006
Joseph A. DiMasi, Success rates for new drugs entering clinical testing in the United States Clinical Pharmacology & Therapeutics. ,vol. 58, pp. 1- 14 ,(1995) , 10.1016/0009-9236(95)90066-7
FRANCIS F. SCHWENTKER, THE TREATMENT OF MENINGOCOCCIC MENINGITIS WITH SULFANILAMIDE Journal of the American Medical Association. ,vol. 108, pp. 1407- 790 ,(1937) , 10.1001/JAMA.1937.02780170025009
Jeffrey L. Fox, Concerns raised over declining antiinfectives R&D. Nature Biotechnology. ,vol. 21, pp. 1255- 1256 ,(2003) , 10.1038/NBT904
John H. Powers, David B. Ross, Erica Brittain, Renata Albrecht, Mark J. Goldberger, The United States Food and Drug Administration and Noninferiority Margins in Clinical Trials of Antimicrobial Agents Clinical Infectious Diseases. ,vol. 34, pp. 879- 881 ,(2002) , 10.1086/339072
Kenneth E. Thorpe, Curtis S. Florence, Peter Joski, Which Medical Conditions Account For The Rise In Health Care Spending Health Affairs. ,vol. 23, pp. 437- 445 ,(2004) , 10.1377/HLTHAFF.W4.437
Arjun Srinivasan, Xiaoyan Song, Ann Richards, Ronda Sinkowitz-Cochran, Denise Cardo, Cynthia Rand, A Survey of Knowledge, Attitudes, and Beliefs of House Staff Physicians From Various Specialties Concerning Antimicrobial Use and Resistance Archives of Internal Medicine. ,vol. 164, pp. 1451- 1456 ,(2004) , 10.1001/ARCHINTE.164.13.1451