Red Cell Membrane Lipid Changes at 3500 m and on Return to Sea Level
作者： Gustavo González , Gloria Celedón , Marcela Escobar , Carlos Sotomayor , Verónica Ferrer
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摘要: Gonzalez, Gustavo, Gloria Celedon, Marcela Escobar, Carlos Sotomayor, Veronica Ferrer, Dixan Benitez, and Claus Behn. Red cell membrane lipid changes at 3500 m on return to sea level. High Alt. Med. Biol. 6:320–326, 2005.—Previous studies have shown that acute hypobaric hypoxia, obtained in a chamber, subsequent reoxygenation, give rise modifications of the erythrocyte dynamics, resulting an increased lateral diffusivity lipids, this was interpreted as result modified lipid–protein interaction. The aim present study determine effect reoxygenation condition individuals after 3 days altitude above Reoxygenation consequence returning Resting blood samples from both conditions were obtained, erythrocytes separated immediately lysed for isolation. We measured bilayer polarity membranes with Laurdan, fluorescent probe. also m...
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