Effects of carnitine and taurine on fatty acid metabolism and lipid accumulation in the liver of cats during weight gain and weight loss.

作者: Wissam H. Ibrahim , Nathanael Bailey , Gregory D. Sunvold , Geza G. Bruckner

DOI: 10.2460/AJVR.2003.64.1265

关键词:

摘要: Objective—To determine the effects of carnitine (Ca) or taurine (Ta) supplementation on prevention lipid accumulation in liver cats. Animals—24 adult Procedure—Cats were fed a weight-gaining diet sufficient n-6 polyunsaturated fatty acids (PUFAs), low long-chain n-3 PUFAs (n-3 LPUFA), and containing corn gluten for 20 weeks. Cats gained at least 30% body weight assigned to 4 weight-reduction diets (6 cats/diet) 7 10 weeks (control diet, control plus Ca, Ta, Ca Ta). Results—Hepatic lipids accumulated significantly during gain loss but not altered by Ta after loss. Carnitine increased LPUFAs hepatic triglycerides, decreased incorporation 13C palmitate into very-low-density lipoprotein plasma ketone bodies. also without altering fat lean mass ratio. Taurine did s...

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