Activation of the hypothalamus-pituitary-adrenal axis by bacterial endotoxins: routes and intermediate signals.
作者： Fred J.H. Tilders , Roel H. DeRuk , Anne-Marie Van Dam , Valerie A.M. Vincent , Karel Schotanus
DOI: 10.1016/0306-4530(94)90010-8
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摘要: … enters the circulation and acts as a hormonal signal. IL-1 may pass fenestrated endothelium … amplify and prolong the intracerebral IL-1 signal. In contrast, high doses of endotoxin given …
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