Monocyte-derived IL-10-secreting dendritic cells in choroid plexus epithelium.

摘要: Choroid plexuses form an interface between peripheral blood and cerebrospinal fluid. Dendritic-like cells have been reported in a few studies of choroid man. Here we used electron microscopy immunophenotyping to precise the morphologic features phenotype these cells. Examination 10 human evidenced intra-epithelial dendritic with clear cytoplasm, reniform nucleus long expansions. These express MHC Class II, CD11b, CD14, CD32, CD68 IL-10, but not CD40, CD80 or CD86, suggesting immunosuppressive role for Their sentinel position could make them participate immunological silence brain.