Inhibition of the lipogenesis in liver and adipose tissue of diet-induced obese C57BL/6 mice by feeding oleic acid-rich sesame oil
作者： Jeong Hoon Pan , Mi Jeong Kim , Jun Ho Kim , Yun Jeong Cho , Han-Seung Shin
DOI: 10.1007/S10068-015-0142-8
关键词:
摘要: The effects of sesame oil (SO) on lipogenic gene expression and lipid metabolism were observed. One percent SO was added into the high-fat diet (HFD) used to feed C57BL/6 male mice for 8 weeks. significantly lowered adipose tissue mass than that control group. In addition, serum hepatic contents markedly lower those Especially, ratio HDL/LDL much higher HFD key enzymes, Ppar-γ, Srebp-1c, Scd-1, Fas, Acc, Lpl, malic enzyme, downregulated in liver fed oil. This study suggests high proportion oleic acid might be strongly associated with lowering profile suppressing expression.
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