Role of Sphingolipids in Regulating the Phospholipase D Pathway and Cell Division
作者： Antonio Gómez-Muñoz , Abdelkarim Abousalham , Yutaka Kikuchi , David W. Waggoner , David N. Brindley
DOI: 10.1007/978-3-662-22425-0_8
关键词:
摘要: This article deals with the interactions of some bioactive glycero-lipids and sphingolipids that control signal transduction, cell activation division. In particular, review will concentrate on consequences agonist-induced hydrolysis phosphatidylcholine sphingomyelin. These two phospholipids are related to each other structurally essentially differ in has a glycerolipid backbone whereas sphingomyelin contains an N-acylated fatty acid linked sphingosine (Table 8.1). The these lipids gives rise lipid analogs such diacylglycerol is ceramide, lysophosphatidate 1-phosphate monoacylglycerol sphingosine. discussion emphasize interaction or “cross-talk” between sphingolipid signaling pathways.
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