Irinotecan/thalidomide in metastatic colorectal cancer.
作者： Rangaswamy Govindarajan
DOI:
关键词:
摘要: The prognosis for patients with metastatic colorectal cancer is poor. Use of irinotecan (CPT-11, Camptosar) results in modest response rates approximately 20% refractory diagnosed this advanced stage disease and offers a side-effect profile that improves on previous standard treatments.
cancernetwork.com参考文章(15)
H C Pitot, D B Wender, M J O'Connell, G Schroeder, R M Goldberg, J Rubin, J A Mailliard, J A Knost, C Ghosh, R J Kirschling, R Levitt, H E Windschitl, Phase II Trial of Irinotecan in Patients With Metastatic Colorectal Carcinoma Journal of Clinical Oncology. ,vol. 15, pp. 2910- 2919 ,(1997) , 10.1200/JCO.1997.15.8.2910
P Rougier, R Bugat, J Y Douillard, S Culine, E Suc, P Brunet, Y Becouarn, M Ychou, M Marty, J M Extra, J Bonneterre, A Adenis, J F Seitz, G Ganem, M Namer, T Conroy, S Negrier, Y Merrouche, F Burki, M Mousseau, P Herait, M Mahjoubi, Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy. Journal of Clinical Oncology. ,vol. 15, pp. 251- 260 ,(1997) , 10.1200/JCO.1997.15.1.251
M L Rothenberg, J R Eckardt, J G Kuhn, H A Burris, J Nelson, S G Hilsenbeck, G I Rodriguez, A M Thurman, L S Smith, S G Eckhardt, G R Weiss, G L Elfring, D A Rinaldi, L J Schaaf, D D Von Hoff, Phase II trial of irinotecan in patients with progressive or rapidly recurrent colorectal cancer. Journal of Clinical Oncology. ,vol. 14, pp. 1128- 1135 ,(1996) , 10.1200/JCO.1996.14.4.1128
Mace L. Rothenberg, John V. Cox, Russell F. DeVore, John D. Hainsworth, Richard Pazdur, Saul E. Rivkin, John S. Macdonald, Charles E. Geyer, John Sandbach, Daniel L. Wolf, J. Scott Mohrland, Gary L. Elfring, Langdon L. Miller, Daniel D. Von Hoff, A multicenter, phase II trial of weekly irinotecan (CPT-11) in patients with previously treated colorectal carcinoma. Cancer. ,vol. 85, pp. 786- 795 ,(1999) , 10.1002/(SICI)1097-0142(19990215)85:4<786::AID-CNCR5>3.0.CO;2-9
Eli D. Ehrenpreis, Sunanda V. Kane, Lawrence B. Cohen, Russell D. Cohen, Stephen B. Hanauer, Thalidomide therapy for patients with refractory Crohn's disease: An open-label trial Gastroenterology. ,vol. 117, pp. 1271- 1277 ,(1999) , 10.1016/S0016-5085(99)70276-3
Nancy Kemeny, Ying Huang, Alfred M. Cohen, Weiji Shi, John A. Conti, Murray F. Brennan, Joseph R. Bertino, Alan D.M. Turnbull, Deidre Sullivan, Jennifer Stockman, Leslie H. Blumgart, Yuman Fong, Hepatic Arterial Infusion of Chemotherapy after Resection of Hepatic Metastases from Colorectal Cancer New England Journal of Medicine. ,vol. 341, pp. 2039- 2048 ,(1999) , 10.1056/NEJM199912303412702
R. J. D'Amato, M. S. Loughnan, E. Flynn, J. Folkman, Thalidomide is an inhibitor of angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 4082- 4085 ,(1994) , 10.1073/PNAS.91.9.4082
Philippe Rougier, Eric Van Cutsem, Emilio Bajetta, Norbert Niederle, Kurt Possinger, Roberto Labianca, Matilde Navarro, Rudolf Morant, Harry Bleiberg, Jacques Wils, Lucile Awad, Patrice Herait, Christian Jacques, Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer The Lancet. ,vol. 352, pp. 1407- 1412 ,(1998) , 10.1016/S0140-6736(98)03085-2
E Van Cutsem, D Cunningham, W.W Ten Bokkel Huinink, C.J.A Punt, C.G Alexopoulos, L Dirix, M Symann, G.H Blijham, P Cholet, G Fillet, C Van Groeningen, J.M Vannetzel, F Levi, G Panagos, C Unger, J Wils, C Cote, C Blanc, P Hérait, H Bleiberg, Clinical activity and benefit of irinotecan (CPT-11) in patients with colorectal cancer truly resistant to 5-fluorouracil (5-FU) European Journal of Cancer. ,vol. 35, pp. 54- 59 ,(1999) , 10.1016/S0959-8049(98)00353-0
Yutaka Takahashi, Susan L Tucker, Yasuhiko Kitadai, Aaryan N Koura, Corazon D Bucana, Karen R Cleary, Lee M Ellis, Vessel Counts and Expression of Vascular Endothelial Growth Factor as Prognostic Factors in Node-Negative Colon Cancer Archives of Surgery. ,vol. 132, pp. 541- 546 ,(1997) , 10.1001/ARCHSURG.1997.01430290087018