Response to crizotinib in a squamous cell lung carcinoma patient harbouring echinoderm microtubule-associated protein-like 4-anaplastic lymphoma translocation: A case report

作者: Wenxian Wang , Zhengbo Song , Yiping Zhang

DOI: 10.1111/1759-7714.12298

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摘要: Squamous cell lung cancer (SCC) presenting with anaplastic lymphoma kinase (ALK) translocation is rare. We present a case of ALK gene translocation-SCC in which remarkable tumor response to crizotinib was achieved after the failure prior chemoradiotherapy. Considering this response, we conclude that testing female non-smokers or any patient unresponsive initial regimen chemotherapy, recommended for SCC patients.

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