Current Advancements and Strategies in Tissue Engineering for Wound Healing: A Comprehensive Review.

摘要: Significance: With an aging population leading to increase in diabetes and associated cutaneous wounds, there is a pressing clinical need improve wound-healing therapies. Recent Advances: Tissue engineering approaches for wound healing skin regeneration have been developed over the past few decades. A review of current literature has identified common themes strategies that are proving successful within field: The delivery cells, mainly mesenchymal stem scaffolds native matrix one such strategy. We overview these give insights into mechanisms aid different scenarios. Critical Issues: discuss importance biomimetic niche, how recapitulating elements microenvironment cells can help direct cell behavior fate. Future Directions: It crucial during continued development tissue repair, close collaboration between engineers clinici...