Phenotyping the Clotting System

摘要: The combined research efforts in our field over the last hundred years made that we now recognise dozens of plasma proteins with a function clotting system and set platelet components is same order. Progress molecular biology such as to have identified some one genes may influence haemostasis thrombosis new comes about every month. Nevertheless phenotype cannot be adequately established. There no simple method gives us clear picture net result activity all those genes, together non-genetic influences (e. g. drugs), on over-all blood at given moment. For century make do times know marginally - if sensitive hypercoagulability mild bleeding disorders. We are used employing different variants for control oral anticoagulants heparin. Some not significantly any type time convenience assumed require control. Standardisation constant problem. But so almost forget they actually serve purpose adequate indicator function, lack test equivalent sugar diabetes or pressure hypertension.