Changes in Hemostatic Indices in Foals Naturally Infected With Strongylus vulgaris

摘要: Abstract Strongylus vulgaris has been found endemic in equine populations subject to parasite control by targeted selective anthelmintic therapy. This study investigated hemostasis foals naturally infected with S. and monitored this response over the course of progressing infection stages. The hemostatic indices D-dimer, antithrombin III (ATIII), fibrinogen, prothrombin time (PT), activated partial thromboplastin were evaluated weekly blood samples for up 50 weeks 12 born into a herd high prevalence . Results compared antibody enzyme-linked immunosorbent assay values all using linear mixed effects model repeated measures total numbers larvae nine at necropsy Pearson correlation. In first week life, significantly different from those observed rest weeks, corresponding previously demonstrated aberrancies neonates. Significant changes seen D-dimer weeks 11–24, 26–27, 30, 39 2, PT 12–13 6, ATIII 15 4. levels statistically associated ( P = .0076) fibrinogen .0004) concentrations. Naturally acquired was suggestive mild activation coagulation, fibrinolysis, inflammation. results may help elucidate pathogenesis endarteritis, thromboembolism, nonstrangulating intestinal ischemia that is horses infection.