CORRELATION OF HLA AND THYROID ANTIBODIES WITH CLINICAL COURSE OF THYROTOXICOSIS TREATED WITH ANTITHYROID DRUGS
作者： W.J. Irvine , R.S. Gray , P.J. Morris , A. Ting
DOI: 10.1016/S0140-6736(77)90833-9
关键词:
摘要: Abstract The prevalence of HLA-B8 in thyrotoxic (Graves' disease) patients who relapsed after withdrawal antithyroid drugs was high (69%) compared with that remained remission (40%) and healthy controls (28%). B8-positive were 1·8 times more likely to relapse drug therapy than B8-negative patients. persistence thyroid microsomal antibodies correlated significantly the presence HLA-B8. This association pronounced remission. From this it might be assumed B8 is also associated T.S.H. (thyroid-stimulating hormone) receptor stimulating antibodies. In view these findings, suggested are typed for HLA, those could given a trial long-term therapy.
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