Adverse effects of iodine thyroid blocking: a systematic review

摘要: (131)I, when released in a radiological or nuclear accident as happened recently Fukushima, Japan, may cause thyroid cancer long-term consequence. Iodine blocking (ITB) is known to reduce the risk of developing cancer. Potential adverse effects ITB have not been systematically investigated so far. This article summarises results review on based systematic literature search scientific medical databases. A meta-analysis was performed identified studies displayed major heterogeneity. The resulted 14 articles relevant topic, reporting mostly surveys, ecological and intervention studies. Only one study from Poland focused (both desired adverse) an following Chernobyl accident. All other reported iodine administration different context. Overall, did reveal severe reactions potassium iodide general public. Since protective measure only applied very specific circumstances, scientifically sound are scarce consequently evidence base weak. assessment relies indirect related areas. contribute ongoing developments pharmacoepidemiology aiming better quantify medications health care interventions including ITB.