The effects of iodine blocking following nuclear accidents on thyroid cancer, hypothyroidism, and benign thyroid nodules: design of a systematic review

作者: Steffen Dreger , Manuela Pfinder , Lara Christianson , Stefan K Lhachimi , Hajo Zeeb

DOI: 10.1186/S13643-015-0106-3

关键词:

摘要: One of the most efficient radiation protection methods to reduce risk adverse health outcomes in case accidental radioactive iodine release is administration potassium (KI). Although KI recommended by WHO’s guidelines for prophylaxis following nuclear accidents and also widely implemented national guidelines, scientific evidence lacks as are mostly based on expert opinions recommendations. Therefore, this study will provide systematically reviewing effects thyroid cancer, hypothyroidism, benign nodules.

参考文章(23)
S Klugbauer, H M Rabes, E Lengfelder, E P Demidchik, High prevalence of RET rearrangement in thyroid tumors of children from Belarus after the Chernobyl reactor accident Oncogene. ,vol. 11, pp. 2459- 2467 ,(1995)
Kerry Joyce, Roman Pabayo, Julia A Critchley, Clare Bambra, Flexible working conditions and their effects on employee health and wellbeing Cochrane Database of Systematic Reviews. ,vol. 2010, ,(2010) , 10.1002/14651858.CD008009.PUB2
Becker Dv, Physiological basis for the use of potassium iodide as a thyroid blocking agent logistic issues in its distribution. Bulletin of the New York Academy of Medicine. ,vol. 59, pp. 1003- 1008 ,(1983)
Bernard Le Guen, Laurent Stricker, Martin Schlumberger, Distributing KI pills to minimize thyroid radiation exposure in case of a nuclear accident in France Nature Clinical Practice Endocrinology & Metabolism. ,vol. 3, pp. 611- 611 ,(2007) , 10.1038/NCPENDMET0593
Evelina Tacconelli, Systematic reviews: CRD's guidance for undertaking reviews in health care Lancet Infectious Diseases. ,vol. 10, pp. 226- ,(2010) , 10.1016/S1473-3099(10)70065-7
M. Jang, H. K. Kim, C. W. Choi, C. S. Kang, Age-dependent potassium iodide effect on the thyroid irradiation by 131I and 133I in the nuclear emergency. Radiation Protection Dosimetry. ,vol. 130, pp. 499- 502 ,(2008) , 10.1093/RPD/NCN068
L. Spallek, L. Krille, C. Reiners, R. Schneider, S. Yamashita, H. Zeeb, Adverse effects of iodine thyroid blocking: a systematic review Radiation Protection Dosimetry. ,vol. 150, pp. 267- 277 ,(2012) , 10.1093/RPD/NCR400
Elliot Sternthal, Leslie Lipworth, Bruce Stanley, Cynthia Abreau, Shih-Lieh Fang, Lewis E. Braverman, Suppression of Thyroid Radioiodine Uptake by Various Doses of Stable Iodide New England Journal of Medicine. ,vol. 303, pp. 1083- 1088 ,(1980) , 10.1056/NEJM198011063031903
Janusz Nauman, Jan Wolff, Iodide prophylaxis in Poland after the chernobyl reactor accident: Benefits and risks The American Journal of Medicine. ,vol. 94, pp. 524- 532 ,(1993) , 10.1016/0002-9343(93)90089-8