Age-dependent potassium iodide effect on the thyroid irradiation by 131I and 133I in the nuclear emergency.

摘要: The initial near-field exposure is primarily through inhalation in a nuclear emergency and the dominant contribution to effective dose comes from radioiodine. Thyroid blockade by oral potassium iodide (KI) efficient practical for public emergency. Age-dependent radioprotective effect of KI on thyroid irradiation (131)I (133)I has been derived using simplified compartment model iodine metabolism WinSAAM program. Administration within 2 h after intake can block uptake significantly, yielding protective 78.9% 74.3%, respectively, adults. mean absorbed doses decrease with age, while effects are similar all age groups.