Reduction of Thyroid Irradiation From 131I by Potassium Iodide

摘要: The prophylactic administration of 100 to 200 mg potassium iodide in anticipation radioactive iodine exposure will largely prevent uptake by the thyroid gland, thereby reducing irradiation dose delivered more than 98%. same amount given at intervals after 131 I absorption is progressively less effective, but still reduces half a delay three hours. suppressive effect one short duration and daily readministration agent required for prolonged protection. extent blockade may be estimated measuring serum inorganic iodide; concentrations greater 10μg /100 cc correlate with marked arrest. Toxicity negligible single ingestion, as this temporary measure reduction immediate hazard, drug must avoided those allergic it.