Pharmacological Profiles of Acute Myeloid Leukemia Treatments in Patient Samples by Automated Flow Cytometry: A Bridge to Individualized Medicine
作者： Teresa A Bennett , Pau Montesinos , Federico Moscardo , David Martinez-Cuadron , Joaquin Martinez
DOI: 10.1016/J.CLML.2013.11.006
关键词:
摘要: We have estimated the pharmacological sensitivity and synergism of 125 individual patient samples for all drugs combination treatments acute myeloid leukemia in context overall population. Each ex vivo profile identifies which patient’s malignant cells are particularly sensitive or resistant, assisting selection individualized treatments. Background: evaluated pharmacology single drug combinations bone marrow from patients with using a novel automated flow cytometrye based platform (ExviTech). improved previous testing 4 innovations: identifying
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