Clastogenic and Anticlastogenic Effect of the Essential Oil from Casearia sylvestris Swart.
作者： Fabrício G. Sousa , Naira F.Z. Schneider , Caroline E. Mendes , Neusa F. de Moura , Rosiane B.N. Denardin
DOI: 10.1080/10412905.2007.9699309
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摘要: Abstract The essential oil composition obtained from the leaves of Casearia sylvestris has been investigated by GC and GC/MS. Thirty-seven compounds were identified in oil. major constituents which β-caryophyllene (27.5%) bicyclogermacrene (24.2%). clastogenic anticlastogenic effect was tested chromosome aberration cells tissue hepatoma Rattus novergicus. three different concentrations C. showed effects. However, tests anticlastogenicity, same protective activity when associated with ethyl methanesulfonate (EMS).
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