The prognostic value of nestin expression in newly diagnosed glioblastoma: report from the Radiation Therapy Oncology Group.
作者： Prakash Chinnaiyan , Meihua Wang , Amyn M Rojiani , Philip J Tofilon , Arnab Chakravarti
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摘要: Background Nestin is an intermediate filament protein that has been implicated in early stages of neuronal lineage commitment. Based on the heterogeneous expression nestin GBM and its potential to serve as a marker for dedifferentiated, perhaps more aggressive phenotype, Radiation Therapy Oncology Group (RTOG) sought determine prognostic value newly diagnosed patients treated prior prospective RTOG clinical trials.
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則雄 荒木, What's going on 放射線 Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, et al; European Organisation for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups; National Cancer Institute of Canada Clinical Trials Group. N Engl J Med. 2005; 352: 987-96. PMID: 15758009.--神経膠腫に対する治療として、放射線治療とテモゾロマイドの併用が世界的な標準的治療となりうることを示唆する論文 Mebio oncology. ,vol. 3, pp. 132- 134 ,(2006)
Takashi Tohyama, VM-Y Lee, LB Rorke, M Marvin, RD McKay, JQ Trojanowski, None, Nestin expression in embryonic human neuroepithelium and in human neuroepithelial tumor cells. Laboratory Investigation. ,vol. 66, pp. 303- 313 ,(1992)
S Hockfield, RD McKay, Identification of major cell classes in the developing mammalian nervous system The Journal of Neuroscience. ,vol. 5, pp. 3310- 3328 ,(1985) , 10.1523/JNEUROSCI.05-12-03310.1985
Walter M Klein, Bryan P Wu, Shuping Zhao, Hong Wu, Andres J P Klein-Szanto, Steven R Tahan, Increased expression of stem cell markers in malignant melanoma Modern Pathology. ,vol. 20, pp. 102- 107 ,(2007) , 10.1038/MODPATHOL.3800720
Davide Schiffer, Andrea Manazza, Ilaria Tamagno, Nestin expression in neuroepithelial tumors. Neuroscience Letters. ,vol. 400, pp. 80- 85 ,(2006) , 10.1016/J.NEULET.2006.02.034
Svetlana Brychtova, Michala Fiuraskova, Alice Hlobilková, Tomas Brychta, Jaroslav Hirnak, Nestin expression in cutaneous melanomas and melanocytic nevi Journal of Cutaneous Pathology. ,vol. 34, pp. 370- 375 ,(2007) , 10.1111/J.1600-0560.2006.00627.X
Ying Mao, Proliferative status of tumor stem cells may be correlated with malignancy grade of human astrocytomas Frontiers in Bioscience. ,vol. 12, pp. 2252- 2259 ,(2007) , 10.2741/2227
J Ehrmann, Nestin as a diagnostic and prognostic marker: immunohistochemical analysis of its expression in different tumours Journal of Clinical Pathology. ,vol. 58, pp. 222- 223 ,(2005) , 10.1136/JCP.2004.021238
Urban Lendahl, Lyle B. Zimmerman, Ronald D.G. McKay, CNS stem cells express a new class of intermediate filament protein. Cell. ,vol. 60, pp. 585- 595 ,(1990) , 10.1016/0092-8674(90)90662-X
Eric C. Holland, Progenitor cells and glioma formation Current Opinion in Neurology. ,vol. 14, pp. 683- 688 ,(2001) , 10.1097/00019052-200112000-00002