Transfer of maternal colostral leukocytes promotes development of the neonatal immune system I. Effects on monocyte lineage cells.

摘要: Although it has been established that maternal leukocytes traffic from colostrum into the neonatal circulation, effects of these cells on immunity are only beginning to be understood. This study examined colostral development and maturation antigen presenting cells. At birth, groups calves received whole or cell-free (CFC) their respective dams. Peripheral blood samples were obtained over first 4 weeks life, expression surface markers associated with cellular activation physiological stress monitored monocyte lineage Calves receiving at birth expressed elevated levels CD11a, CD11c, CD14, compared (C). had an number monocytes in peripheral during 2 however, lower CD25 MHC class I colostrum. The most significant differences marker occurred within 7 days life.