摘要: For the last 100 years, tuberculin skin test (TST) has been only diagnostic tool available for latent TB infection (LTBI) and no biomarker per se is to diagnose presence of LTBI. With introduction M. tuberculosis-specific IFN-gamma release assays (IGRAs), a new area in vitro immunodiagnostic tests LTBI based on readout become reality. In this review, we discuss existing evidence clinical usefulness IGRAs indefinite number potential biomarkers that can be used improve diagnosis infection. We also present early data suggesting monocyte-derived chemokine inducible protein-10 may useful as novel immunodiagnosis
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