Can interferon-gamma or interferon-gamma-induced-protein-10 differentiate tuberculosis infection and disease in children of high endemic areas?

作者: Mohammed Ahmed Yassin , Roberta Petrucci , Kefyalew Taye Garie , Gregory Harper , Isabel Arbide

DOI: 10.1371/JOURNAL.PONE.0023733

关键词: Differential diagnosisHuman immunodeficiency virus (HIV)DiseaseImmunologyInterferon gammaChildhood tuberculosisVirologySputumTuberculosisReference valuesMedicine

摘要: Background Diagnosis of childhood tuberculosis (TB) is difficult in high TB burden settings. Interferon-gamma-induced protein 10 (IP10) has been suggested as a marker infection and disease, but its ability to differentiate the two conditions remains uncertain.

参考文章(40)
Navneet Kaur Dhillon, Fuwang Peng, Richard M. Ransohoff, Shilpa Buch, PDGF Synergistically Enhances IFN-γ-Induced Expression of CXCL10 in Blood-Derived Macrophages: Implications for HIV Dementia Journal of Immunology. ,vol. 179, pp. 2722- 2730 ,(2007) , 10.4049/JIMMUNOL.179.5.2722
JA Crump, C Seshadri, LO Uiso, J Ostermann, H Diefenthal, HJ Shao, HY Chu, DM Asmuth, NM Thielman, JA Bartlett, Low sensitivity of T-cell based detection of tuberculosis among HIV co-infected Tanzanian in-patients. East African Medical Journal. ,vol. 85, pp. 442- 449 ,(2008) , 10.4314/EAMJ.V85I9.117085
Bernhard Moser, Pius Loetscher, Lymphocyte traffic control by chemokines Nature Immunology. ,vol. 2, pp. 123- 128 ,(2001) , 10.1038/84219
P. Godfrey-Faussett, K. Shanaube, B. Kosloff, H. Ayles, A. Schaap, M. Moyo, P. de Haas, A. Devendra, E. Raby, Intra-assay reliability and robustness of QuantiFERON®-TB Gold In-Tube test in Zambia. International Journal of Tuberculosis and Lung Disease. ,vol. 14, pp. 828- 833 ,(2010)
M Huie, M Rigaud, H Pollack, Jennifer Lighter, C-H Peng, Chemokine IP-10: an adjunct marker for latent tuberculosis infection in children. International Journal of Tuberculosis and Lung Disease. ,vol. 13, pp. 731- 736 ,(2009)
Elizabeth Whittaker, Andrea Gordon, Beate Kampmann, Is IP-10 a Better Biomarker for Active and Latent Tuberculosis in Children than IFNγ? PLOS ONE. ,vol. 3, ,(2008) , 10.1371/JOURNAL.PONE.0003901
Elisabetta Ferrero, Priscilla Biswas, Katuscia Vettoretto, Marina Ferrarini, Mariagrazia Uguccioni, Luca Piali, Biagio Eugenio Leone, Bernhard Moser, Claudio Rugarli, Ruggero Pardi, Macrophages exposed to Mycobacterium tuberculosis release chemokines able to recruit selected leucocyte subpopulations: focus on γδ cells Immunology. ,vol. 108, pp. 365- 374 ,(2003) , 10.1046/J.1365-2567.2003.01600.X
Morten Ruhwald, Pernille Ravn, Biomarkers of latent TB infection Expert Review of Respiratory Medicine. ,vol. 3, pp. 387- 401 ,(2009) , 10.1586/ERS.09.31