EPIDEMIOLOGY OF SMEAR - NEGATIVE TUBERCULOSIS IN IBADAN, NIGERIA
作者： AO Kehinde , H Dada‐Adegbola
DOI: 10.4314/AJID.V7I1.4
关键词:
摘要: Inadequate case detection has been identified as one of the reasons for high burden tuberculosis (TB) in world especially poor resourced countries Africa and Asia. This retrospective laboratory study involving review specimens processed at TB Department Medical Microbiology Parasitology, University College Hospital, Ibadan, Nigeria was carried out over a period five years (January 2006-December 2010) to access epidemiology smear-negative TB. Of 3468 processed, 2,175 (62.7%) were from males while lower percentage (37.3%)1293 females, giving M:F = 1:0.37. Over half specimens, 2,046 (59.0%) patients aged 21 60 years, 392 (11.3%) 11 20 825 (23.8%) above 205 (5.9%) age 1-10 years. Most 2,663 (76.8%) sputum 201 (5.8%) gastric washings. Three hundred nine (8.9%) smear positive culture positive. However, 83 (2.6%) 3159 (false negative) 66 (21.4%) 309 smear-positive negative positive). The majority, 3010 (86.8%) both tests. false 51 samples representing (61.4%), 19 (22.9%) washings 13 (15.7%) extra-pulmonary sites (CSF, aspirates, ascitic fluids, etc). findings 2.6% but this reveals that addition microscopy suspected cases is necessary diagnostic /confirmatory tool tuberculosis.
sci-hub.se 参考文章(10)
O'Brien R, Foulds J, New tools for the diagnosis of tuberculosis: the perspective of developing countries. International Journal of Tuberculosis and Lung Disease. ,vol. 2, pp. 778- 783 ,(1998)
V.R. Aber, B.W. Allen, D.A. Mitchison, P. Ayuma, E.A. Edwards, A.B. Keyes, Laboratory studies on isolated positive cultures and the efficiency of direct smear examination Tubercle. ,vol. 61, pp. 123- 133 ,(1980) , 10.1016/0041-3879(80)90001-X
Kamran Siddiqi, Marie-Laurence Lambert, John Walley, Clinical diagnosis of smear-negative pulmonary tuberculosis in low-income countries: the current evidence Lancet Infectious Diseases. ,vol. 3, pp. 288- 296 ,(2003) , 10.1016/S1473-3099(03)00609-1
J.R. Starke, Childhood tuberculosis: treatment strategies and recent advances. Paediatric Respiratory Reviews. ,vol. 2, pp. 103- 112 ,(2001) , 10.1053/PRRV.2001.0117
Stephen D Lawn, Gavin Churchyard, Epidemiology of HIV-associated tuberculosis. Current Opinion in Hiv and Aids. ,vol. 4, pp. 325- 333 ,(2009) , 10.1097/COH.0B013E32832C7D61
Elizabeth L. Corbett, Catherine J. Watt, Neff Walker, Dermot Maher, Brian G. Williams, Mario C. Raviglione, Christopher Dye, The Growing Burden of Tuberculosis Archives of Internal Medicine. ,vol. 163, pp. 1009- 1021 ,(2003) , 10.1001/ARCHINTE.163.9.1009
L. Mtei, M. Matee, O. Herfort, M. Bakari, C. R. Horsburgh, R. Waddell, B. F. Cole, J. M. Vuola, S. Tvaroha, B. Kreiswirth, K. Pallangyo, C. F. von Reyn, High Rates of Clinical and Subclinical Tuberculosis among HIV-Infected Ambulatory Subjects in Tanzania Clinical Infectious Diseases. ,vol. 40, pp. 1500- 1507 ,(2005) , 10.1086/429825
O A Ogunlade, O M Sogaolu, O M Ige, Pattern of presentation of tuberculosis and the hospital prevalence of tuberculosis and HIVco-infection in University College Hospital, Ibadan: a review of five years (1998 - 2002). African journal of medicine and medical sciences. ,vol. 34, pp. 329- 333 ,(2005)
C M Parry, Sputum smear negative pulmonary tuberculosis. Tropical Doctor. ,vol. 23, pp. 145- 146 ,(1993) , 10.1177/004947559302300402
T C Kim, T Kim, K M Heatwole, D F Rochester, R S Blackman, Acid-fast bacilli in sputum smears of patients with pulmonary tuberculosis. Prevalence and significance of negative smears pretreatment and positive smears post-treatment. The American review of respiratory disease. ,vol. 129, pp. 264- 268 ,(1984)