Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases

作者: Elaine Y. Lin , Joan G. Jones , Ping Li , Liyin Zhu , Kathleen D. Whitney

DOI: 10.1016/S0002-9440(10)63568-7

关键词:

摘要: Animal models are powerful tools to analyze the mechanism of the induction of human breast cancer. Here we report a detailed analysis of mammary tumor progression in one …

参考文章(48)
Yi Li, Wendy P Hively, Harold E Varmus, Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer. Oncogene. ,vol. 19, pp. 1002- 1009 ,(2000) , 10.1038/SJ.ONC.1203273
Ivan Bièche, Rosette Lidereau, Genetic alterations in breast cancer. Genes, Chromosomes and Cancer. ,vol. 14, pp. 227- 251 ,(1995) , 10.1002/GCC.2870140402
Ann S. Tsukamoto, Rudolf Grosschedl, Raphael C. Guzman, Tristram Parslow, Harold E. Varmus, Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell. ,vol. 55, pp. 619- 625 ,(1988) , 10.1016/0092-8674(88)90220-6
A. C. Andres, C. A. Schonenberger, B. Groner, L. Hennighausen, M. LeMeur, P. Gerlinger, Ha-ras oncogene expression directed by a milk protein gene promoter: tissue specificity, hormonal regulation, and tumor induction in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 84, pp. 1299- 1303 ,(1987) , 10.1073/PNAS.84.5.1299
Calvin D Roskelley, Mina J Bissell, The dominance of the microenvironment in breast and ovarian cancer. Seminars in Cancer Biology. ,vol. 12, pp. 97- 104 ,(2002) , 10.1006/SCBI.2001.0417
I. G. Maroulakou, M. Anver, L. Garrett, J. E. Green, Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 11236- 11240 ,(1994) , 10.1073/PNAS.91.23.11236
Valérie Gouon-Evans, Marc E. Rothenberg, Jeffrey W. Pollard, Postnatal mammary gland development requires macrophages and eosinophils. Development. ,vol. 127, pp. 2269- 2282 ,(2000) , 10.1242/DEV.127.11.2269
C T Guy, R D Cardiff, W J Muller, Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Molecular and Cellular Biology. ,vol. 12, pp. 954- 961 ,(1992) , 10.1128/MCB.12.3.954
Xiaoling Xu, Kay-Uwe Wagner, Denise Larson, Zoë Weaver, Cuiling Li, Thomas Ried, Lothar Hennighausen, Anthony Wynshaw-Boris, Chu-Xia Deng, Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. Nature Genetics. ,vol. 22, pp. 37- 43 ,(1999) , 10.1038/8743