Inhibition of pancreatic adenocarcinoma cell growth by lovastatin
作者： Shoichiro Sumi , R.Daniel Beauchamp , Courtney M. Townsend , Tatsuo Uchida , Manabu Murakami
DOI: 10.1016/0016-5085(92)90032-T
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摘要: … At a 75+g/mL concentration, the survival fraction was markedly decreased, especially by 24 hours of exposure. This dose is SO-fold higher than the 2.5 pg/mL that resulted in reversible …
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Cancer statistics, 1989. CA: A Cancer Journal for Clinicians. ,vol. 39, pp. 3- 20 ,(1989) , 10.3322/CANJCLIN.39.1.3
V Quesney-Huneeus, H A Galick, M D Siperstein, S K Erickson, T A Spencer, J A Nelson, The dual role of mevalonate in the cell cycle. Journal of Biological Chemistry. ,vol. 258, pp. 378- 385 ,(1983) , 10.1016/S0021-9258(18)33268-X
K P Fairbanks, L D Witte, D S Goodman, Relationship between mevalonate and mitogenesis in human fibroblasts stimulated with platelet-derived growth factor. Journal of Biological Chemistry. ,vol. 259, pp. 1546- 1551 ,(1984) , 10.1016/S0021-9258(17)43443-0
P. Pour, M. Takahashi, J. Althoff, T. Donnelly, Sequential Alteration of the Pancreas during Carcinogenesis in Syrian Hamsters by N-Nitrosobis(2-oxopropyl)amine Cancer Research. ,vol. 37, pp. 4602- 4607 ,(1977)
A.J. Habenicht, J.A. Glomset, R. Ross, Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and swiss 3T3 cells stimulated to divide by platelet-derived growth factor. Journal of Biological Chemistry. ,vol. 255, pp. 5134- 5140 ,(1980) , 10.1016/S0021-9258(19)70760-1
M A Tainsky, L A Eader, M K Oskarsson, D G Blair, C S Cooper, G F Vande Woude, Characterization of human transforming genes from chemically transformed, teratocarcinoma, and pancreatic carcinoma cell lines. Cancer Research. ,vol. 44, pp. 1- 10 ,(1984)
Elizabeth Taparowsky, Kenji Shimizu, Mitchell Goldfarb, Michael Wigler, Structure and activation of the human N-ras gene Cell. ,vol. 34, pp. 581- 586 ,(1983) , 10.1016/0092-8674(83)90390-2
Osoa KANEKO, Yoko HAZAMA-SHIMADA, Akira ENDO, Inhibitory Effects on Lipid Metabolismn in Cultured Cells of ML‐236B, a Potent Inhibitor of 3‐Hydroxt‐3‐methylglutaryl‐Cornzyme‐A Reductase FEBS Journal. ,vol. 87, pp. 313- 321 ,(1978) , 10.1111/J.1432-1033.1978.TB12380.X
Akira Endo, Masao Kuroda, Kazuhiko Tanzawa, Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme a reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity FEBS Letters. ,vol. 72, pp. 323- 326 ,(1976) , 10.1016/0014-5793(76)80996-9
Carol J. Quaife, Carl A. Pinkert, David M. Ornitz, Richard D. Palmiter, Ralph L. Brinster, Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice Cell. ,vol. 48, pp. 1023- 1034 ,(1987) , 10.1016/0092-8674(87)90710-0