Comparative ultrastructural studies of the alterations to mouse lung parenchyma during Trichinella spiralis or Toxocara canis infection.

摘要: Summary Trichinella spiralis and Toxocara canis larvae migrated through the lung induced many alterations in parenchyma. Using electron microscopy, we identified described histopathological changes. These changes resulted from mechanical damage or local inflammatory reactions provoked by larvae. The pattern of was between 6 12 days post-infection (DPI) with T. spiralis larvae, 21 28 DPI T. canis. ultrastructural studies demonstrated that migrating lungs evoked mainly destruction type I epithelial cells, lamellar bodies cells extracellular alveolar lining layer. severity these dependent on number infective (400 800 larvae) possibly result In contrast, infection T. canis initiated eosinophilic perivasculitis vasculitis as well macrophage accumulation lung, which were additionally impacted numerous crystalloid inclusions macrophages. Trichinella different pathological infected mice.