Method for preparing salts of 6-chloropurine

作者: Henry Bader , Yunn H. Chiang

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摘要: There is described a novel method for preparing and isolating salts of 6-chloropurine strong acids. According to the hypoxanthine reacted with phosphorus oxychloride in presence an organic base form 6-chloropurine, solvent added reaction mixture latter acid salt which then isolated. In preferred embodiment freed from water, preferably base. another aminated various amines.

参考文章(3)
Yasuo Fujimoto, Masao Naruse, Process for the purification of 6-halogenopurine ,(1966)
Lloyd N. Ferguson, Textbook of organic chemistry Van Nostrand. ,(1965)
Kawashima Hideaki, Takenishi Tadao, Kumashiro Izumi, Method of preparing 2, 6-dichloropurine and 2, 6-dichloropurine ribofuranosyl ,(1964)