Hepatitis C therapy with long term remission after renal transplantation.

作者: S. Bunnapradist , F. Fabrizi , J. Vierling , P. Martin , A. Moudgil

DOI: 10.1177/039139880202501211

关键词:

摘要: Hepatitis C virus infection (HCV) is common in patients with end-stage renal disease (ESRD) and long observation periods have shown the detrimental effect of HCV on patient graft survival after transplantation. At present, interferon most important agent for treatment hepatitis ESRD; however, limited information exists concerning long-term response who undergo transplantation successful antiviral therapy. We describe evolution a dialysis was successfully treated alpha then underwent He received aggressive immunosuppression during induction phase allograft rejection; regular screening showed complete absence biochemical virological relapse over 6-year post-transplantation period. conclude that can offer excellent selected C. Alternative strategies newer agents are currently under active investigation.

参考文章(26)
Sameer Huraib, Aamir Iqbal, Danlami Tanimu, Abdulkader Abdullah, Sustained virological and histological response with pretransplant interferon therapy in renal transplant patients with chronic viral hepatitis C. American Journal of Nephrology. ,vol. 21, pp. 435- 440 ,(2001) , 10.1159/000046646
Lionel Rostaing, Jacques Izopet, Emmanuel Baron, Michel Duffaut, Jacqueline Puel, Dominique Durand, Treatment of chronic hepatitis C with recombinant interferon alpha in kidney transplant recipients. Transplantation. ,vol. 59, pp. 1426- 1431 ,(1995) , 10.1097/00007890-199505270-00012
Stanislas Pol, Marie Laure Chaix, Valérie Laffitte, Catherine Buffet, Pierre H. Bernard, Claude Degott, Françoise Carnot, Philippe Chaumet Riffaud, Sylvie Chevret, Françoise Degos, The tolerance and efficacy of interferon‐α in haemodialysis patients with HCV infection: a multicentre, prospective study Nephrology Dialysis Transplantation. ,vol. 16, pp. 1017- 1023 ,(2001) , 10.1093/NDT/16.5.1017
Paul Koenig, Wolfgang Vogel, Florian Umlauft, Katharina Weyrer, Rupert Prommegger, Karl Lhotta, Ulrich Neyer, Hans-Krister Stummvoll, Kurt Gruenewald, Interferon treatment for chronic hepatitis C virus infection in uremic patients. Kidney International. ,vol. 45, pp. 1507- 1509 ,(1994) , 10.1038/KI.1994.197
Xian-Hui He, Pang-Chui Shaw, Siu-Cheung Tam, Reducing the immunogenicity and improving the in vivo activity of trichosanthin by site-directed pegylation. Life Sciences. ,vol. 65, pp. 355- 368 ,(1999) , 10.1016/S0024-3205(99)00257-X
J. Izopet, L. Rostaing, F. Moussion, L. Alric, M. Dubois, H. Ton That, J. L. Payen, M. Duffaut, D. Durand, J. M. Suc, J. Puel, High Rate of Hepatitis C Virus Clearance in Hemodialysis Patients after Interferon-α Therapy The Journal of Infectious Diseases. ,vol. 176, pp. 1614- 1617 ,(1997) , 10.1086/517339
Fabrizio Fabrizi, Paul Martin, Claudio Ponticelli, Hepatitis C virus infection and renal transplantation American Journal of Kidney Diseases. ,vol. 38, pp. 919- 934 ,(2001) , 10.1053/AJKD.2001.28576
Daniele Marcelli, David Stannard, Ferruccio Conte, Philip J. Held, Francesco Locatelli, Friedrich K. Port, ESRD patient mortality with adjustment for comorbid conditions in Lombardy (Italy) versus the United States Kidney International. ,vol. 50, pp. 1013- 1018 ,(1996) , 10.1038/KI.1996.403
Stanislas Pol, Valérie Thiers, Françoise Carnot, Brigitte Zins, Raffaella Romeo, Pierre Berthelot, Christian Bréchot, Efficacy and tolerance of α-2b interferon therapy on HCV infection of hemodialyzed patients Kidney International. ,vol. 47, pp. 1412- 1418 ,(1995) , 10.1038/KI.1995.198