Current Understanding on EGFR and Wnt/β-Catenin Signaling in Glioma and Their Possible Crosstalk

作者: I *Paul , S *Bhattacharya , A Chatterjee , MK Ghosh. , *equal contribution

DOI: 10.1177/1947601913503341

关键词:

摘要: Glioblastoma multiformes (GBMs) are extensively heterogeneous at both cellular and molecular levels. Current therapeutic strategies include targeting of key signaling molecules using …

参考文章(200)
Nives Pećina-Šlaus, Tomislav Kokotović, Reno Hrašćan, Davor Tomas, Tamara Nikuševa Martić, Vesna Kušec, AXIN-1 Protein Expression and Localization in Glioblastoma Collegium Antropologicum. ,vol. 35, pp. 101- 106 ,(2011)
Jorge L Eller, Sharon L Longo, Michele M Kyle, Daniel Bassano, Daniel J Hicklin, Gregory W Canute, None, Anti-epidermal growth factor receptor monoclonal antibody cetuximab augments radiation effects in glioblastoma multiforme in vitro and in vivo. Neurosurgery. ,vol. 56, pp. 155- 162 ,(2005) , 10.1227/01.NEU.0000145865.25689.55
Thomas Klockgether, Gary Landreth, Jessica Koenigsknecht, Michael T. Heneka, Thomas Zander, Jürgen A. Kraus, Christian Grommes, Uwe Schlegel, Douglas Feinstein, Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARγ Journal of Neurochemistry. ,vol. 81, pp. 1052- 1060 ,(2002) , 10.1046/J.1471-4159.2002.00899.X
Fengming Lan, Xiao Yue, Lei Han, Xubo Yuan, Zhendong Shi, Kai Huang, Yang Yang, Jian Zou, Junxia Zhang, Tao Jiang, Peiyu Pu, Chunsheng Kang, Antitumor effect of aspirin in glioblastoma cells by modulation of β-catenin/T-cell factor-mediated transcriptional activity. Journal of Neurosurgery. ,vol. 115, pp. 780- 788 ,(2011) , 10.3171/2011.5.JNS113
Benjamin E. Alderete, C. David James, Robert B. Jenkins, Wanguo Liu, Lori Frederick, PTEN/MMAC1 Mutations and EGFR Amplification in Glioblastomas Cancer Research. ,vol. 57, pp. 5254- 5257 ,(1997)
John H. Sampson, Gamal Akabani, Gary E. Archer, Darell D. Bigner, Mitchel S. Berger, Allan H. Friedman, Henry S. Friedman, James E. Herndon II, Sandeep Kunwar, Steve Marcus, Roger E. McLendon, Alison Paolino, Kara Penne, James Provenzale, Jennifer Quinn, David A. Reardon, Jeremy Rich, Timothy Stenzel, Sandra Tourt-Uhlig, Carol Wikstrand, Terence Wong, Roger Williams, Fan Yuan, Michael R. Zalutsky, Ira Pastan, Progress Report of a Phase I Study of the Intracerebral Microinfusion of a Recombinant Chimeric Protein Composed of Transforming Growth Factor (TGF)-α and a Mutated form of the Pseudomonas Exotoxin Termed PE-38 (TP-38) for the Treatment of Malignant Brain Tumors Journal of Neuro-oncology. ,vol. 65, pp. 27- 35 ,(2003) , 10.1023/A:1026290315809
Lene Uhrbom, Eric C. Holland, Modeling Gliomagenesis with Somatic Cell Gene Transfer using Retroviral Vectors Journal of Neuro-oncology. ,vol. 53, pp. 297- 305 ,(2001) , 10.1023/A:1012208314436
Dexing Fang, David Hawke, Yanhua Zheng, Yan Xia, Jill Meisenhelder, Heinz Nika, Gordon B. Mills, Ryuji Kobayashi, Tony Hunter, Zhimin Lu, Phosphorylation of β-Catenin by AKT Promotes β-Catenin Transcriptional Activity * Journal of Biological Chemistry. ,vol. 282, pp. 11221- 11229 ,(2007) , 10.1074/JBC.M611871200
Diane C. Slusarski, Victor G. Corces, Randall T. Moon, Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling Nature. ,vol. 390, pp. 410- 413 ,(1997) , 10.1038/37138
W Chearwae, J J Bright, PPARγ agonists inhibit growth and expansion of CD133+ brain tumour stem cells British Journal of Cancer. ,vol. 99, pp. 2044- 2053 ,(2008) , 10.1038/SJ.BJC.6604786