Interventional Radiology for Colorectal Liver Metastases

作者: Frederic Deschamps , Maxime Ronot , Maximiliano Gelli , Jerome Durand-Labrunie , Melodie Tazdait

DOI: 10.1007/S11888-020-00449-0

关键词:

摘要: To discuss the pivotal role of Interventional radiology (IR) for management colorectal liver metastases (CRLM). IR has three main objectives treatment CRLM: Radiofrequency ablation (RFA) is most reported percutaneous technique and provides high local control rates that exceed 90% small (< 3 cm). Novel technologies such as microwave could help overcome some limitations RFA. Liver non-amenable to radical can, because their arterial supply, be targeted with hepatic infusion chemotherapy (HAIC) or selective internal radiation therapy (SIRT). HAIC demonstrated encouraging response in patients who have previously failed intravenous adjuvant therapies decrease post-operative recurrence rates. Although large SIRT trials are negative, there a benefit terms progression-free survival when used first-line combination systemic well selected advanced disease justifies further interest this technique. More recent developments, stereotactic body administration immunotherapies, require contribution IR. growing becoming standard care metastases. Further innovations likely improve its impact.

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