Risk assessment in cancer patients with fever and neutropenia: a prospective, two-center validation of a prediction rule.

摘要: PURPOSEThe study was undertaken to validate a clinical model for predicting the medical risk of cancer patients with fever and neutropenia.PATIENTS AND METHODSA consecutive sample 444 neutropenia (granulocyte count less than 500/microL) at two hospitals, specialized referral center university-affiliated general hospital, studied identify characteristics in first 24 hours that predict subsequent serious complications during hospital stay. To control bias, major factors were subject blinded review.RESULTSSerious occurred 34% identified prior study, including inpatient status (group I), outpatients independent comorbidity II), or uncontrolled III), compared 5% remaining IV) (P .000001). Two group IV transient asympto...